November 27, 2023 by Thomas Sander

Let's introduce Alipheron!

Welcome to Alipheron AG, the cheminformatics company that focuses on Ultra-large Combinatorial Space (ULCS) searches. As a strong believer into open-source technology, we integrate, enhance, and advance open source projects in the field of drug discovery.

One of the key open-source software packages endorsed and supported by Alipheron is DataWarrior, probably the most widely used open-source cheminformatics platforms for end-users world-wide. DataWarrior combines interactive visualization of large datasets with chemical intelligence. It allows predicting properties directly from the chemical structure, supports dimension reduction, space visualization, data filtering and merging, access to relevant databases, and full automation. Its cheminformatics capabilities include combinatorial enumeration, evolutionary de-novo compound design, activity cliff analysis, R-group deconvolution, conformer generation, protein ligand docking, and much more. It is used by more than 100'000 scientists in more than 130 countries.

Integrating DataWarrior into your enterprise software landscape is seamless, thanks to its fully Java-based architecture compatible with all major operating systems. Whether used as a standalone system or integrated into enterprise data processing pipelines, Alipheron offers custom database plugins to facilitate integration with a range of SQL databases, including cloud-based serverless databases like Athena. Additionally, inquire about our support for NoSQL databases.

In tandem with our commitment to open-source excellence, Alipheron proudly supports OpenChemLib, a cheminformatics framework with broad coverage of diverse cheminformatics functionality.

Leveraging this foundation, Alipheron introduces powerful tools for virtual screening and ULCS searches. Alipheron partners with ultra-large combinatorial space providers offering a platform to search trillions of molecules to find the next innovative drug discovery lead molecules, which can be ordered for immediate synthesis at the space providers.

Embark on a journey of innovation with Alipheron, where scientific rigor meets open-source ingenuity, shaping the future of drug discovery.